代表性研究成果
1.Han, Y., Sarkar, H., Xu, Z., Lopez-Darwin, S., Wei, Y., Hang, X., Liu, F., Tran, K., Wang, W., Miller, J.M., DeCoste, C. J., Blohm, D. S., Satcher, R. L., Zhang, X. H., Kang, Y.. (2025). Tumors hijack macrophages for iron supply to promote bone metastasis and anemia. Cell 188, 6335-6354.e6326. 10.1016/j.cell.2025.08.013. (Featured Article)
2.Xu, Z., Liu, F., Ding, Y., Pan, T., Wu, Y.H., Han, Y., Liu, J., Bado, I.L., Zhang, W., Wu, L., et al. (2026). Unbiased niche labeling maps immune-excluded niche in bone metastasis. Cell. 10.1016/j.cell.2026.04.009.
3.Bartman, C.R., Weilandt, D.R., Shen, Y., Lee, W.D., Han, Y., TeSlaa, T., Jankowski, C.S.R., Samarah, L., Park, N.R., da Silva-Diz, V., et al. (2023). Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature 614, 349-357. 10.1038/s41586-022-05661-6.
4.Bai, M.#, Han, Y.#, Wu, Y., Liao, J., Li, L., Wang, L., Li, Q., Xing, W., Chen, L., Zou, W., and Li, J. (2019). Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development. PLoS Biol 17, e3000350. 10.1371/journal.pbio.3000350. (#co-first author)
5.Dai, Q.#, Xie, F.#, Han, Y.#, Ma, X., Zhou, S., Jiang, L., Zou, W., and Wang, J. (2017). Inactivation of Regulatory-associated Protein of mTOR (Raptor)/Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling in Osteoclasts Increases Bone Mass by Inhibiting Osteoclast Differentiation in Mice. J Biol Chem 292, 196-204. 10.1074/jbc.M116.764761. (#co-first author)
6.Dai, Q.#, Han, Y.#, Xie, F., Ma, X., Xu, Z., Liu, X., Zou, W., and Wang, J. (2018). A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation. J Vis Exp. 10.3791/56468. (#co-first author)
7.Feng, H.#, Xing, W.#, Han, Y.#, Sun, J., Kong, M., Gao, B., Yang, Y., Yin, Z., Chen, X., Zhao, Y., et al. (2020). Tendon-derived cathepsin K-expressing progenitor cells activate Hedgehog signaling to drive heterotopic ossification. J Clin Invest 130, 6354-6365. 10.1172/jci132518. (#co-first author)